Protein Modification Reagents
Medchemexpress LLC Br-PEG4-THP | 1803547-60-5 | 341.24 | 100 MG
Br-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is for research use only and not sold to patients.
- CAS number: 1803547-60-5
- Molecular weight: 341.24
- Chemical formula: C13H25BrO5
- Appearance: Liquid
- Color: Colorless to light yellow
- Shipping conditions: Room temperature in continental US
- Storage conditions for pure form: -20°C for 3 years, 4°C for 2 years
- Storage conditions in solvent: -80°C for 6 months, -20°C for 1 month
Cole-Parmer White peg for modular stainless steel drying racks, 4"L
Removable snap-in plugs and pegs come in packs of six.
Chemscene ChemScene | DL-dithiothreitol | 100G | CS-3035 | 0.98 | 578517| MFCD00004877 | 154.25
ChemScene | DL-dithiothreitol | 100G | CS-3035 | 0.98 | 578517| MFCD00004877 | 154.25
Echelon Biosciences Research Labs Plasmin Substrate - 5 mg,
Plasmin Substrate - 5mg , D-Val-Leu-Lys-AFC Category/Application: Enzyme Substrates This item is non returnable
Abcam Recombinant human Prolyl Endopeptidase protein, 20UG
Recombinant human Prolyl Endopeptidase protein is a Human Full Length protein, in the 2 to 710 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, FuncS.
Protein/ Peptide/ Enzyme Synonyms: PEP, PREP, Prolyl endopeptidase, PE, Post-proline cleaving enzyme
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Azide-PEG4-VC-PAB-doxorubicin | 99.6% | 1222.25 g/mol | C57H75N9O21 | 100 MG
Azide-PEG4-VC-PAB-doxorubicin is an azide-functionalized drug-linker conjugate that links the cytotoxic agent doxorubicin to a PEG4-VC-PAB linker for use in antibody-drug conjugate synthesis and click chemistry applications.
- High purity (99.62%).
- Molecular weight 1222.25 g/mol.
- Chemical formula C57H75N9O21.
- Orange to red solid appearance.
- Storage: powder at -20°C (long term) or 4°C (short term); in solvent at -80°C or -20°C as recommended.
- Available as solid (1-100 mg) and 10 mM solution in DMSO.
Medchemexpress LLC Mal-PEG4-PFP ester | 1415800-42-8 | MFCD28556926 | >98.0% | 511.39 g/mol | C21H22F5NO8 | 100 MG
Mal-PEG4-PFP ester is a non-cleavable antibody-drug conjugate (ADC) linker containing a maleimide thiol-reactive group, a four-unit polyethylene glycol (PEG4) spacer, and a pentafluorophenyl (PFP) activated ester for bioconjugation. It is supplied as a solid for research use.
- Non-cleavable maleimide PEG4 linker
- PFP ester for activated carboxyl conjugation
- Suitable for ADC and bioconjugation workflows
- Solid powder form, typically supplied at 100 mg
- Intended for research use only
Medchemexpress LLC Amino-PEG4-GGFG-Dxd | 2879227-88-8 | 1088.14 g·mol⁻1 | C53H66FN9O15 | 5 MG
Amino-PEG4-GGFG-Dxd is a drug-linker conjugate intended for use in antibody-drug conjugate (ADC) synthesis. It couples a DXd (deruxtecan) payload to a GGFG peptide-based linker via a PEG4 spacer and provides an amino functional handle for conjugation to antibodies.
- drug-linker conjugate for ADC synthesis
- contains a DXd payload linked via a cleavable GGFG peptide linker
- includes a PEG4 spacer to improve solubility and spacing
- features an amino functional handle for conjugation chemistry
- available in small milligram quantities for research use
- molecular weight 1088.14 g·mol⁻1, formula C53H66FN9O15
Medchemexpress LLC Mal-PEG4-NHS ester | 1325208-25-0 | MFCD20230464 | 99.4% | 442.42 g/mol | C19H26N2O10 | 100 MG
Mal-PEG4-NHS ester is a heterobifunctional PEG linker containing a maleimide group and an N-hydroxysuccinimide (NHS) ester; it is used for conjugating thiol-containing molecules to amines and for ADC and bioconjugation applications.
- Maleimide reacts with thiols for site-specific conjugation.
- NHS ester reacts with primary amines under mild conditions.
- PEG4 spacer increases solubility and reduces steric hindrance.
- High reported purity suitable for research use.
- Available in small laboratory quantities for convenient use.
Medchemexpress LLC Mal-PEG4-VC-PAB-DMEA-PNU-159682 | 2259318-52-8 | 1559.62 | C74H98N10O27 | 10 MG
Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a cleavable antibody-drug conjugate (ADC) drug-linker conjugate that combines a Mal-PEG4-VC-PAB cleavable linker with the cytotoxic payload DMEA-PNU-159682 for use in ADC research and drug-conjugate development.
- Cleavable ADC drug-linker conjugate suitable for antibody-drug conjugate synthesis.
- Contains a maleimide functional group for thiol conjugation.
- High molecular weight for payload delivery and characterization.
- Supplied in small research pack sizes for controlled studies.
- Store solid at -20°C, protect from light, and keep under inert gas; follow solvent storage recommendations for solutions.
Medchemexpress LLC Amino-PEG4-Val-Cit-PAB-MMAE | 1492056-71-9 | 99.9% | 1370.71 | C69H115N11O17 | 1 MG
Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable 4-unit PEG antibody-drug conjugate (ADC) linker used to attach cytotoxic payloads such as MMAE to antibodies during ADC synthesis. It contains a Val-Cit dipeptide cleavable spacer and a para-aminobenzyl (PAB) self-immolative spacer with a PEG4 solubilizing linker, providing controlled payload release in target cells.
- Cleavable Val-Cit peptide spacer enabling enzyme-triggered release
- PAB self-immolative spacer for efficient payload release
- PEG4 linker improves solubility and spacer length
- High reported purity (approximately 99.9%)
- Soluble in DMSO and compatible with common in vivo formulations
Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 1-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl)-PEG4-SS-NHS ester | 95.0% | 737.84 | C31H43N7O10S2 | 10 MG
Methyltetrazine-PEG4-SS-NHS ester is a cleavable PEG4-based methyltetrazine-functionalized N-hydroxysuccinimide ester for bioconjugation and click-chemistry applications. It provides a tetrazine reactive handle for inverse electron-demand Diels-Alder labeling, and contains a disulfide cleavable spacer and PEG4 linker to improve solubility and enable reductive release.
- Purity 95.0% (NMR).
- Pink to red oil appearance.
- Molecular weight 737.84.
- Chemical formula C31H43N7O10S2.
- Contains a disulfide cleavable linker and a PEG4 spacer.
- Provides a tetrazine handle for IEDDA bioconjugation.
- Storage: pure form at -20°C (stable for 3 years); in solvent -80°C for 6 months, -20°C for 1 month.
- Tested by 1H NMR; for research use only.