Protein Modification Reagents
Medchemexpress LLC DSPE-PEG-FITC | 95.0% | 600 Da (average) | 25 MG
DSPE-PEG-FITC (MW 600) is a fluorescein-labeled PEGylated phospholipid used to introduce surface fluorescence into liposomes and nanoparticles. It is an amphiphilic conjugate that forms micelles in aqueous solution and enables tracking and imaging of lipid-based carriers in biological studies (Ex/Em = 488/525 nm).
- Amphiphilic PEG-lipid that forms micelles in aqueous solution.
- Provides surface fluorescence for liposome and nanoparticle tracking.
- Fluorescein label with excitation/emission 488/525 nm suitable for common fluorescence instruments.
- Average molecular weight about 600 Da for consistent labeling behavior.
- Solid, light yellow material with reported purity ~95.0%.
- Store protected from light; stable frozen in solvent for extended storage.
Medchemexpress LLC Propargyl-PEG4-5-nitrophenyl carbonate | 1422540-81-5 | 98.2% | 397.38 | 50 MG
Propargyl-PEG4-5-nitrophenyl carbonate is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It also functions as a click chemistry reagent, featuring an Alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Features an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Exploits ubiquitin-proteasome system for selective protein degradation
Medchemexpress LLC m-PEG15-amine | 2745717-94-4 | 99.9% | 691.85 | 25 MG
m-PEG15-amine (CAS No.: 2745717-94-4) is a high-purity PEG-based PROTAC linker with a molecular formula of C31H65NO15 and a molecular weight of 691.85.
- High purity of 99.9%
- Appears as a colorless to light yellow oil
- Store at -20°C under nitrogen
- When in solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
Medchemexpress LLC Br-PEG4-THP | 1803547-60-5 | 341.24 | 100 MG
Br-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is for research use only and not sold to patients.
- CAS number: 1803547-60-5
- Molecular weight: 341.24
- Chemical formula: C13H25BrO5
- Appearance: Liquid
- Color: Colorless to light yellow
- Shipping conditions: Room temperature in continental US
- Storage conditions for pure form: -20°C for 3 years, 4°C for 2 years
- Storage conditions in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Cy3-PEG2-endo-BCN bromide | >98.0% | 843.93 Da | C47H63BrN4O5 | 10 MG
Cy3-PEG2-endo-BCN bromide is a Cyanine 3-derived fluorescent reagent with a PEG2 linker and an endo-BCN reactive moiety, supplied as the bromide salt. It is optimized for catalyst-free strain-promoted alkyne-azide cycloaddition (SPAAC) to label azide-bearing biomolecules for fluorescence imaging, biochemical assays, and probe synthesis.
- Enables catalyst-free SPAAC click chemistry with azide-functionalized molecules.
- PEG2 linker improves solubility and reduces steric hindrance in conjugation.
- Bromide salt form simplifies handling and storage.
- Strong orange-red fluorescence suitable for imaging and detection.
- Ideal for preparing fluorescent bioconjugates and probes.
eMolecules Tos-PEG10-Tos | Broadpharm | 109635-64-5 | MFCD25372003 | 722.860 | C32H50O14S2 | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1 | 1g | 229582273
Tos-PEG10-Tos | Broadpharm | 109635-64-5 | MFCD25372003 | 722.860 | C32H50O14S2 | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1 | 1g | 229582273
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG5-CH2COOH | 50 g | CAS 635287-26-2 | InChIKey LNIFRTLAPAPKAG-UHFFFAOYSA-N
Fmoc-NH-PEG5-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 635287-26-2
- MDL: No data
- InChIKey: LNIFRTLAPAPKAG-UHFFFAOYSA-N
- Molecular Weight: 517.575
- Molecular Formula: C27H35NO9
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid
- SMILES: O=C(COCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
eMolecules Fmoc-PEG5-NHS ester | 1402080-11-8 | MFCD28976702 | 1g
Broadpharm | Fmoc-PEG5-NHS ester | 1g | 343283761 | BP-22808 | 98.000 | 1402080-11-8 | MFCD28976702 | 628.675 | C32H40N2O11
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Medchemexpress LLC Mal-PEG4-propargyl | 1262681-30-0 | 99.68% | 311.33 | 100 MG
Mal-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. For research use only.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Alkyne group
- Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
eMolecules PC DBCO-PEG3-biotin | 1807512-43-1 | MFCD28505553 | >96.0% | 10 MG
PC DBCO-PEG3-biotin | 1807512-43-1 | MFCD28505553 | >96.0% | 10 MG
Medchemexpress LLC Mal-PEG2-VCP-NB | 2395887-69-9 | 98.3% | 783.78 g/mol | C36H45N7O13 | 50 MG
Mal-PEG2-VCP-NB is a cleavable antibody-drug conjugate (ADC) linker featuring a maleimide reactive group, a two-unit polyethylene glycol (PEG2) spacer, and a VCP NB moiety. It is supplied as a research chemical for ADC conjugation and formulation studies.
- Cleavable ADC linker containing a maleimide reactive group.
- Two-unit PEG spacer to improve solubility and flexibility.
- VCP NB moiety for payload attachment.
- Purity 98.25% and molecular weight 783.78 g/mol.
- Soluble in DMSO (100 mg/mL); sonication may be required.
- Supplied as a 50 mg powder; store at 4°C under nitrogen; in solution store -80°C up to 6 months.
Medchemexpress LLC Azido-PEG4-azide | 182760-73-2 | ≥97.0% | 288.30 | 250 MG
Azido-PEG4-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This click chemistry reagent features an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PEG-based PROTAC linker
- Used for PROTAC synthesis
- Click chemistry reagent
- Contains an Azide group
- Participates in CuAAc reactions with alkyne groups
- Undergoes SPAAC reactions with DBCO or BCN groups